The aim was to identify early target genes of the senescence-associated transcription factor: ORS1. For this purpose we used DEX-inducible system and studied the expression profile 5h after treatment using Affymetrix microarray.
ORS1, an H₂O₂-responsive NAC transcription factor, controls senescence in Arabidopsis thaliana.
Specimen part
View SamplesHigh-density kinetic analysis of the metabolomic and transcriptomic response of Arabidopsis to temperature and light
High-density kinetic analysis of the metabolomic and transcriptomic response of Arabidopsis to eight environmental conditions.
Specimen part, Time
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Double-stranded microRNA mimics can induce length- and passenger strand-dependent effects in a cell type-specific manner.
Cell line
View SamplesExperiment 1 - miR-155 and miR-199 Phenotype
Double-stranded microRNA mimics can induce length- and passenger strand-dependent effects in a cell type-specific manner.
Cell line
View SamplesExperiment 2 - MiRNA mimics have a length and passenger strand specific effect
Double-stranded microRNA mimics can induce length- and passenger strand-dependent effects in a cell type-specific manner.
Cell line
View SamplesTranscriptome study of 2 Saccharomyces cerevisiae W303 derivatives, one carrying GFP (control) and one carrying aSyn-GFP
Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.
Specimen part, Disease, Cell line
View SamplesTranscription profiling of Arabidopsis mutant ron1-1 vs the wild type Ler
The RON1/FRY1/SAL1 gene is required for leaf morphogenesis and venation patterning in Arabidopsis.
Specimen part
View SamplesMicroarray-based expression profiling of BRCA2 knockout and isogenic wild type HCT116 human colorectal cancer cells
Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells.
Cell line
View SamplesAnalysis of the response to arginine of the Escherichia coli K-12 transcriptome by microarray hybridization and real-time quantitative PCR provides a first coherent quantitative picture of the ArgR-mediated repression of arginine biosynthesis and uptake genes. Transcriptional repression was shown to be the major control mechanism of the biosynthetic genes, leaving only limited room for additional transcriptional or post-transcriptional regulations. The art genes coding for the specific arginine uptake system are subject to ArgR-mediated repression,
The arginine regulon of Escherichia coli: whole-system transcriptome analysis discovers new genes and provides an integrated view of arginine regulation.
No sample metadata fields
View SamplesDHPM-thiones rescue Ab-mediated toxicity in a metal-dependent manner that strongly synergizes with clioquinol, a known metal-binding and cytoprotective compound. RNA-seq experiments reveal a modest, yet specific effect on metal-responsive genes that do not change with the inactive control compound. Overall design: Treatment of biological replicates with DMSO, 0.8 uM clioquinol, or 20 uM 10{3,3,1} (DHPM-thione) for ~6 hours prior to harvesting of cells and isolation of total RNA.
Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism.
Cell line, Subject
View Samples