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Accession IconSRP044198

HENMT1-mediated piRNA methylation is required for adult piRNA stability, TE-repression and spermatogenesis

Organism Icon Mus musculus
Sample Icon 2 Downloadable Samples
Technology Badge IconIllumina HiSeq 2000

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HENMT1 is required for the 2’ O-methylation of mammalian piRNAs. The absence of such methylation leads to a reduction in both piRNA bulk and length, and ultimately male infertility.
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