Expression data of wild type and C-DGCR8 KO cones at different timepoints [array] - refine.bio

GSE58493

Mus musculus

20 Downloadable Samples

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Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

We have analyzed gene expression in cone photoreceptors isolated from wild type and C-DGCR8 (DiGeorge Syndrome Critical Region Gene 8) KO mice at five different time points to get a mechanistic inside into the altered molecular pathways after microRNAs depletion.

PubMed ID

Publication Title

miRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function.

Total Samples

20

Submitter’s Institution

Authors

Busskamp V, Krol J, Nelidova D, Daum J, Szikra T, Tsuda B, Jüttner J, Farrow K, Scherf BG, Alvarez CP, Genoud C, Sothilingam V, Tanimoto N, Stadler M, Seeliger M, Stoffel M, Filipowicz W, Roska B

Source Repository

Gene Expression Omnibus (GEO)

P50_wt cones, replicate 1 [array]

cone photoreceptors

P50_C-DGCR8 KO cones, replicate 2 [array]

cone photoreceptors

P90_wt cones, replicate 1 [array]

cone photoreceptors

P50_C-DGCR8 KO cones, replicate 1 [array]

cone photoreceptors

P50_wt cones, replicate 2 [array]

cone photoreceptors

P40_wt cones, replicate 2 [array]

cone photoreceptors

P40_C-DGCR8 KO cones, replicate 2 [array]

cone photoreceptors

P30_wt cones, replicate 1 [array]

cone photoreceptors

P30_wt cones, replicate 2 [array]

cone photoreceptors

P60_wt cones, replicate 2 [array]

cone photoreceptors

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