Differential gene expression between ERRa KO and WT mouse kidneys

Build and Download Custom Datasets

refine.bio helps you build ready-to-use datasets with normalized transcriptome data from all of the world’s genetic databases.

GSE16623

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Estrogen-related receptor (ERR) alpha is an orphan nuclear receptor highly expressed in the kidneys. ERRalpha is implicated in renal sodium and potassium homeostasis and blood pressure regulation. We used microarray analysis to identify differentially expressed genes in ERR alpha knockout mice kidneys versus wild-type. The results provide insight on the roles of ERRalpha in the kidney.

PubMed ID

19901197

Publication Title

Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway.

Total Samples

Submitter’s Institution

McGill University

Authors

Tremblay AM, Dufour CR, Ghahremani M, Reudelhuber TL, Giguère V

Source Repository

Gene Expression Omnibus (GEO)

No rows found