Timecourse: MB neurons at the onset and early steps of axon pruning

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GSE10012

Drosophila melanogaster

16 Downloadable Samples

Affymetrix Drosophila Genome Array (drosgenome1)

Submitter Supplied Information

Description

Drosophila mushroom body (MB) neurons undergo axon pruning during metamorphosis through a process of localized degeneration of specific axon branches. Developmental axon degeneration is initiated at the onset of metamorphosis by the pre-pupal rise in the steroid hormone ecdysone. This study identifies genes that alter their expression in MB neurons at the onset and early steps of axon pruning.

PubMed ID

18550751

Publication Title

Genomic analysis of Drosophila neuronal remodeling: a role for the RNA-binding protein Boule as a negative regulator of axon pruning.

Total Samples

Submitter’s Institution

Stanford University

Authors

Hoopfer ED, Penton A, Watts RJ, Luo L

Source Repository

Gene Expression Omnibus (GEO)

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